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SH3RF2 Antikörper (Cy3)

SH3RF2 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal Cy3
Produktnummer ABIN1419467
  • Target Alle SH3RF2 Antikörper anzeigen
    SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 28
    • 2
    Kaninchen
    Klonalität
    • 28
    • 2
    Polyklonal
    Konjugat
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SH3RF2 Antikörper ist konjugiert mit Cy3
    Applikation
    • 30
    • 14
    • 12
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RNF158
    Isotyp
    IgG
    Top Product
    Discover our top product SH3RF2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))
    Andere Bezeichnung
    RNF158 (SH3RF2 Produkte)
    Synonyme
    MGC81405 antikoerper, SH3RF2 antikoerper, HEPP1 antikoerper, POSHER antikoerper, PPP1R39 antikoerper, RNF158 antikoerper, 2310046K19 antikoerper, 9130023G24Rik antikoerper, AI452083 antikoerper, Ppp1r39 antikoerper, Posh2 antikoerper, SH3 domain containing ring finger 2 antikoerper, SH3 domain containing ring finger 2 S homeolog antikoerper, SH3RF2 antikoerper, sh3rf2.S antikoerper, sh3rf2 antikoerper, Sh3rf2 antikoerper
    Hintergrund

    Synonyms: Heart protein phosphatase 1-binding protein, HEPP1, Putative E3 ubiquitin protein ligase SH3RF2, Putative E3 ubiquitin-protein ligase SH3RF2, RING finger protein 158, SH3 domain containing RING finger protein 2, SH3 domain-containing RING finger protein 2, SH3R2_HUMAN, Sh3rf2.

    Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. SH3RF2 (SH3 domain containing ring finger 2), also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains. Via its RING-type zinc finger domain, SH3RF2 binds an E2 ubiquitin-conjugating enzyme. This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. Due to alternative splicing events, SH3RF2 is expressed as two different isoforms.

    Gen-ID
    153769
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