C18orf1 Antikörper (AA 1-50) (Cy3)
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- Target Alle C18orf1 Antikörper anzeigen
- C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
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Bindungsspezifität
- AA 1-50
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser C18orf1 Antikörper ist konjugiert mit Cy3
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human C18orf1
- Isotyp
- IgG
- Top Product
- Discover our top product C18orf1 Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
- Andere Bezeichnung
- C18orf1 (C18orf1 Produkte)
- Synonyme
- C18orf1 antikoerper, 8230401C20Rik antikoerper, A430083H02 antikoerper, A430108L08Rik antikoerper, D18Ertd653e antikoerper, D330030L18Rik antikoerper, low density lipoprotein receptor class A domain containing 4 antikoerper, LDLRAD4 antikoerper, Ldlrad4 antikoerper
- Hintergrund
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Synonyms: C18orf1, Low-density lipoprotein receptor class A domain-containing protein 4, LDLRAD4
Background: Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.
- Gen-ID
- 753
- UniProt
- O15165
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