HECA Antikörper (AA 260-310) (Cy5)

Produktnummer ABIN1422048

Produktdetails anti-HECA Antikörper (Cy5)

Target: HECA (Headcase Homolog (HECA))

Bindungsspezifität: AA 260-310

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HECA Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HECA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HECA

Target: HECA (Headcase Homolog (HECA))

Andere Bezeichnung: HECA (HECA Produkte)

Synonyme: HECA antikoerper, si:dkey-34f16.2 antikoerper, HDC antikoerper, HDCL antikoerper, HHDC antikoerper, dJ225E12.1 antikoerper, Gm869 antikoerper, hdc homolog, cell cycle regulator antikoerper, Heca antikoerper, HECA antikoerper, heca antikoerper

Hintergrund:

Synonyms: HDCL, Gm869, HDC, HDC_HUMAN, Headcase homolog Drosophila, Headcase protein homolog, HECA, hHDC.

Background: HECA, also known as headcase homolog, HDC, HDCL or HHDC, is a 543 amino acid mammalian homolog of the Drosophila headcase protein, a highly basic, cytplasmic peptide that plays a role in mitotic re-entry during adult morphogenesis. Expressed in a variety of tissues with highest expression in thymus, spleen and heart, HECA is thought to play a role in the development of epithelial tube networks in lung tissue and may also be involved in the pathogenesis of lung cancer. The gene encoding HECA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6 % of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Gen-ID: 51696

UniProt: Q9UBI9