ITM2A Antikörper (AA 73-123) (Cy5)

Produktnummer ABIN1422066

Produktdetails anti-ITM2A Antikörper (Cy5)

Target: ITM2A (Integral Membrane Protein 2A (ITM2A))

Bindungsspezifität: AA 73-123

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITM2A Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ITM2A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ITM2A

Target: ITM2A (Integral Membrane Protein 2A (ITM2A))

Andere Bezeichnung: ITM2A (ITM2A Produkte)

Synonyme: itm2aa antikoerper, e25a antikoerper, itm2ab antikoerper, bricd2a antikoerper, BRICD2A antikoerper, E25A antikoerper, AW108051 antikoerper, Bricd2a antikoerper, E25 antikoerper, Itm2 antikoerper, integral membrane protein 2A antikoerper, integral membrane protein 2A S homeolog antikoerper, integral membrane protein 2A L homeolog antikoerper, Integral membrane protein 2A antikoerper, Itm2a antikoerper, itm2a.S antikoerper, ITM2A antikoerper, itm2a.L antikoerper, itm2a antikoerper

Hintergrund:

Synonyms: E25A, BRICD2A, Integral membrane protein 2A, Protein E25, ITM2A, UNQ603/PRO1189

Background: The type II integral membrane (ITM2) protein family consists of three members ITM2A (also designated E25), ITM2B and ITM2C. ITM2A expression is high in osteogenic and lymphoid tissues, while both ITM2B and ITM2C are expressed in brain. Mutations in the ITM2B gene can lead to familial British dementia (fbd), and autosomal dominant disease characterized by progressive dementia, spasticity, and cerebellar ataxia, or familial Danish dementia (fdd), an autosomal dominant disorder characterized by cataracts, deafness, progressive ataxia, and dementia. The ITM2A 263-amino acid protein contains an N-terminal cytosolic domain, an uncleaved signal anchor sequence, and a tyrosine-rich C-terminal domain. Human ITM2A shares 91 % homology with mouse ITM2A.

Gen-ID: 9452

UniProt: O43736