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ANKLE2 Antikörper (Cy3)

ANKLE2 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal Cy3
Produktnummer ABIN1422275
  • Target Alle ANKLE2 Produkte
    ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))
    Reaktivität
    • 26
    • 18
    • 18
    • 1
    Human, Maus, Ratte
    Wirt
    • 23
    • 3
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ANKLE2 Antikörper ist konjugiert mit Cy3
    Applikation
    • 26
    • 12
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ANKLE2
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))
    Andere Bezeichnung
    ANKLE2 (ANKLE2 Produkte)
    Synonyme
    KIAA0692 antikoerper, LEMD7 antikoerper, Lem4 antikoerper, 1110001J12Rik antikoerper, AI661024 antikoerper, D5Ertd585e antikoerper, RGD1310191 antikoerper, ankyrin repeat and LEM domain containing 2 antikoerper, ANKLE2 antikoerper, Ankle2 antikoerper
    Hintergrund

    Synonyms: ANKL2_HUMAN, ANKLE 2, ANKLE2, ankyrin repeat and LEM domain containing 2, Ankyrin repeat and LEM domain-containing protein 2, LEM domain containing 7, LEMD 7, LEMD7.

    Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKLE2 (ankyrin repeat and LEM domain containing 2), also known as LEMD7, is a 938 amino acid single-pass membrane protein containing an ANK repeat and a LEM domain. Exsiting as two isoforms produced by alternative splicing events, the gene encoding ANKLE2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

    Gen-ID
    23141
    UniProt
    Q86XL3
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