ANKLE2 Antikörper (Cy3)
-
- Target Alle ANKLE2 Produkte
- ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ANKLE2 Antikörper ist konjugiert mit Cy3
-
Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ANKLE2
- Isotyp
- IgG
-
-
- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))
- Andere Bezeichnung
- ANKLE2 (ANKLE2 Produkte)
- Synonyme
- KIAA0692 antikoerper, LEMD7 antikoerper, Lem4 antikoerper, 1110001J12Rik antikoerper, AI661024 antikoerper, D5Ertd585e antikoerper, RGD1310191 antikoerper, ankyrin repeat and LEM domain containing 2 antikoerper, ANKLE2 antikoerper, Ankle2 antikoerper
- Hintergrund
-
Synonyms: ANKL2_HUMAN, ANKLE 2, ANKLE2, ankyrin repeat and LEM domain containing 2, Ankyrin repeat and LEM domain-containing protein 2, LEM domain containing 7, LEMD 7, LEMD7.
Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKLE2 (ankyrin repeat and LEM domain containing 2), also known as LEMD7, is a 938 amino acid single-pass membrane protein containing an ANK repeat and a LEM domain. Exsiting as two isoforms produced by alternative splicing events, the gene encoding ANKLE2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
- Gen-ID
- 23141
- UniProt
- Q86XL3
-