FAM189B Antikörper (Cy5)

Produktnummer ABIN1422504

Produktdetails anti-FAM189B Antikörper (Cy5)

Target: FAM189B (Family with Sequence Similarity 189, Member B (FAM189B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM189B Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FAM189B

Target: FAM189B (Family with Sequence Similarity 189, Member B (FAM189B))

Andere Bezeichnung: C1orf2 (FAM189B Produkte)

Synonyme: C1orf2 antikoerper, COTE1 antikoerper, 1110013L07Rik antikoerper, family with sequence similarity 189 member B antikoerper, family with sequence similarity 189, member B antikoerper, FAM189B antikoerper, Fam189b antikoerper

Hintergrund:

Synonyms: Chromosome 1 open reading frame 2, COTE1, F189B_HUMAN, FAM189B, Family with sequence similarity 189 member B, Hypothetical protein LOC10712, Protein COTE1, Protein FAM189B.

Background: COTE1, also known as FAM189B (family with sequence similarity 189, member B), is a 668 amino acid multi-pass membrane protein that is widely expressed and belongs to the FAM189 family. Existing as two alternatively spliced isoforms, COTE1 is encoded by a gene that maps to human chromosome 1q22. As the largest human chromosome, chromosome 1 spans about 260 million base pairs and makes up approximately 8 % of the human genome. Hutchinson-Gilford progeria, a rare aging disorder, is associated with the LMNA gene which is located on chromosome 1. Familial adenomatous polyposis, Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gen-ID: 10712