AHCTF1 Antikörper (AA 470-520) (Cy5)

Produktnummer ABIN1423074

Produktdetails anti-AHCTF1 Antikörper (Cy5)

Target: AHCTF1 (AT Hook Containing Transcription Factor 1 (AHCTF1))

Bindungsspezifität: AA 470-520

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AHCTF1 Antikörper ist konjugiert mit Cy5

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ELYS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu AHCTF1

Target: AHCTF1 (AT Hook Containing Transcription Factor 1 (AHCTF1))

Andere Bezeichnung: ELYS (AHCTF1 Produkte)

Hintergrund:

Synonyms: ahctf1, AT hook containing transcription factor 1, DKFZp434N093, ELYS, AT-hook-containing transcription factor 1, ELYS transcription factor like protein TMBS62, ELYS_HUMAN, Embryonic large molecule derived from yolk sac, MST108, MSTP108, Protein ELYS, Protein MEL-28, Putative AT-hook-containing transcription factor 1, TMBS62.

Background: ELYS is a protein of the nuclear matrix that contains one AT hook DNA-binding domain. ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division. Nuclear pores span the nuclear envelope and act as gated aqueous channels to regulate the transport of macromolecules between the nucleus and cytoplasm, from individual proteins and RNAs to entire viral genomes. The A.T. hook near the C-terminus of likely indicates ELYS can function as a transcription factor which may play a specific role in hematopoietic tissues. It also may play a role in early embryo development, as ELYS is critical for the survival of inner cells of the blastocyst.

Gen-ID: 25909

UniProt: Q8WYP5