C11orf46 Antikörper (Cy3)

Produktnummer ABIN1423385

Produktdetails anti-C11orf46 Antikörper (Cy3)

Target: C11orf46 (Chromosome 11 Open Reading Frame 46 (C11orf46))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C11orf46 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C11ORF46

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu C11orf46

Target: C11orf46 (Chromosome 11 Open Reading Frame 46 (C11orf46))

Andere Bezeichnung: C11ORF46 (C11orf46 Produkte)

Synonyme: MGC115732 antikoerper, ARF7EP antikoerper, C11orf46 antikoerper, dJ299F11.1 antikoerper, 2700007P21Rik antikoerper, 4930448O08Rik antikoerper, RGD1311463 antikoerper, C15H11orf46 antikoerper, ARL14EP antikoerper, ADP ribosylation factor like GTPase 14 effector protein L homeolog antikoerper, ADP ribosylation factor like GTPase 14 effector protein antikoerper, ADP-ribosylation factor-like 14 effector protein antikoerper, ADP-ribosylation factor like GTPase 14 effector protein antikoerper, arl14ep.L antikoerper, arl14ep antikoerper, ARL14EP antikoerper, Arl14ep antikoerper

Hintergrund:

Synonyms: Chromosome 11 open reading frame 46, DJ299F11.1, FLJ38968, Hypothetical protein LOC120534, Uncharacterized protein C11orf46, AL14E_HUMAN.

Background: C11orf46, also known as FLJ38968 or dJ299F11.1, is a 260 amino acid protein that is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Gen-ID: 120534