C12orf53 Antikörper (Cy3)

Produktnummer ABIN1423499

Produktdetails anti-C12orf53 Antikörper (Cy3)

Target: C12orf53 (Chromosome 12 Open Reading Frame 53 (C12orf53))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C12orf53 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C12ORF53

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu C12orf53

Target: C12orf53 (Chromosome 12 Open Reading Frame 53 (C12orf53))

Andere Bezeichnung: C12ORF53 (C12orf53 Produkte)

Synonyme: C12orf53 antikoerper, PANP antikoerper, leda-1 antikoerper, PILR alpha associated neural protein antikoerper, PIANP antikoerper

Hintergrund:

Synonyms: Chromosome 12 open reading frame 53, DKFZp547D2210, Hypothetical protein LOC196500, Uncharacterized protein C12orf53, PIANP_HUMAN.

Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf53 gene product has been provisionally designated C12orf53 pending further characterization.

Gen-ID: 196500