LMBR1 Antikörper (PE-Cy5)

Produktnummer ABIN1436614

Produktdetails anti-LMBR1 Antikörper (PE-Cy5)

Target: LMBR1 (Limb Region 1 Homolog (LMBR1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMBR1 Antikörper ist konjugiert mit PE-Cy5

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LMBR1/DIF14

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LMBR1

Target: LMBR1 (Limb Region 1 Homolog (LMBR1))

Andere Bezeichnung: DIF14 (LMBR1 Produkte)

Synonyme: im:7156444 antikoerper, LMBR1 antikoerper, ACHP antikoerper, C7orf2 antikoerper, DIF14 antikoerper, PPD2 antikoerper, TPT antikoerper, ZRS antikoerper, RGD1563910 antikoerper, 1110048D14Rik antikoerper, AU017641 antikoerper, limb region 1 homolog (mouse) antikoerper, limb development membrane protein 1 antikoerper, limb region 1 antikoerper, lmbr1 antikoerper, LMBR1 antikoerper, Lmbr1 antikoerper

Hintergrund:

Synonyms: ACHP, C7orf2, D 14, D14, Dferentiation related gene 14, Dferentiation related gene 14 protein, Dferentiation-related gene 14 protein, FLJ11665, Limb region 1 homolog mouse, Limb region 1 homolog, Limb region 1 protein, Limb region 1 protein homolog, LMBR 1, LMBR1, LMBR1_HUMAN, PPD 2, PPD2, TPT.

Background: LMBR1 is a 490 amino acid multi-pass membrane protein that is widely expressed with strongest expression in heart and pancreas. Belonging to the LIMR family, LMBR1 shares 95 % sequence identity with the mouse protein and may play crucial role in the evolution of limb and skeletal system. LMBR1 is critical for expression of sonic hedgehog (Shh) in the developing posterior limb bud mesenchyme. Mutations in the gene encoding LMBR1 is the cause of several rare conditions such as acheiropody (ACHP) and syndactyly type 4 (SDYT4). ACHP is an autosomal recessive inherited disorder characterized by bilateral congenital amputations of the hands and feet. LMBR1L (limb region 1 protein homolog-like), also known as LIMR (Lipocalin-1-interacting membrane receptor), is a 489 amino acid multi-pass membrane protein that is thought to act as a receptor for Lipocalin-1 and may also assist in its endocytosis.

Molekulargewicht: 55kDa

Gen-ID: 64327