PDIA3 Antikörper (C-Term)

Produktnummer ABIN1440039

Produktdetails anti-PDIA3 Antikörper

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Affe, Meerschweinchen, Rind (Kuh), Kaninchen, Schwein, Hamster, Pferd, Schaf, Ziege, Avian, Cat, Huhn, Esel

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PDIA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Detects a band of 60 kDa by Western blot in the following canine, human, monkey, mouse, rat whole cell lysates.

Produktmerkmale: PDIA3 protein disulfide isomerase family A, member 3

Aufreinigung: epitope affinity purified

Immunogen: Purified recombinante peptide derived from within residues 300 aa to the C-terminus of human ERP57 produced in E. coli.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 2 mg/mL

Buffer: Polyclonal antibody supplied as a 200 µL (2 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide

Handhabung: The antibody solution should be gently mixed before use.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.

Referenzen für anti-PDIA3 Antikörper (ABIN1440039)

Alenquer, Vale-Costa, Etibor, Ferreira, Sousa, Amorim: "Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites." in: Nature communications, Vol. 10, Issue 1, pp. 1629, (2019) (PubMed).

Details zu PDIA3

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Andere Bezeichnung: ERP57 (PDIA3 Produkte)

Hintergrund: This endoplasmic reticulum protein interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. It has disulfide isomerase activity and complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Synonyms: 58 kDa glucose regulated protein, 58 kDa microsomal protein, disulfide isomerase ER 60, endoplasmic reticulum resident protein 57, endoplasmic reticulum resident protein 60, ER protein 57, ER protein 60, ER protein 61, ERP57, ERp60, ERp61, glucose regulated protein 58 Kd, GRP57, GRP58, HsT17083, P58, PDIA3, phospholipase C alpha, PI PLC, protein disulfide isomerase A3 antibody.
Ensembl identifier: ENSG00000167004

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis