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BAFF Antikörper

TNFSF13B Reaktivität: Human WB, FACS, IHC (p) Wirt: Maus Monoclonal 1D6 unconjugated
Produktnummer ABIN1449224
  • Target Alle BAFF (TNFSF13B) Antikörper anzeigen
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    Reaktivität
    • 118
    • 30
    • 29
    • 2
    • 2
    • 2
    Human
    Wirt
    • 77
    • 38
    • 17
    • 10
    Maus
    Klonalität
    • 88
    • 54
    Monoklonal
    Konjugat
    • 73
    • 18
    • 10
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BAFF Antikörper ist unkonjugiert
    Applikation
    • 77
    • 57
    • 49
    • 30
    • 15
    • 15
    • 13
    • 13
    • 11
    • 10
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody reacts with human BAFF/BLyS.
    Immunogen
    Human BAFF/BLyS transfectant
    Klon
    1D6
    Isotyp
    IgG1
    Top Product
    Discover our top product TNFSF13B Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Protein A agarose, PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Upon receipt, store (in aliqouts) at -20 °C.
  • Target
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    Andere Bezeichnung
    CD257 / BAFF (TNFSF13B Produkte)
    Hintergrund
    BAFF (B cell-activating factor belonging to the TNF family) is a membrane protein expressed by dendritic cells, monocytes, macrophages, follicular dendritic cells, activated T cells, activated neutrophils, and malignant B cells. BAFF, also known as BLyS (B lymphocyte stimulator), is a potent B cell growth factor. Proteolytic cleavage can result in the release of a soluble trimeric BAFF which binds to the BAFF receptor, BCMA and TACI. The release of soluble BAFF is regulated by IFN-? and to a lesser extent IL-10. BAFF protects B cells from apoptosis and increases the expression of anti-apoptotic proteins Bcl-2 and Bcl-xL.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4
    Gen-ID
    10673
    NCBI Accession
    NP_001139117
    UniProt
    Q9Y275
    Pathways
    NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response
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