Histone H4 Antikörper

Produktnummer ABIN1449238

Produktdetails anti-Histone H4 Antikörper

Target: Histone H4

Reaktivität: Human, Maus, Ratte, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Histone H4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Spezifität: This antibody reacts with Histone H4.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat, Hamster

Aufreinigung: Protein A agarose

Immunogen: Protein fraction extracted from the mitotic chromosome

Klon: C14691

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Details zu Histone H4

Target: Histone H4

Abstract: Histone H4 Produkte

Hintergrund: The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multiple different post-transcriptional modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. Acetylation of histone H4 plays a primary role in the structural changes that mediate enhanced binding of transcription factors to their recognition sites within nucleosomes. It has been suggested that acetylated Histone H4 also is involved in heightened activation of the transcription of male X chromosomes, and that Histone H4 stimulates glucose transport activity in rat skeletal muscle.Synonyms: H4/A, H4FA, HIST1H4

Molekulargewicht: 11 kDa

Gen-ID: 121504

NCBI Accession: NP_001029249

UniProt: P62805