Transferrin Receptor Antikörper (FITC)
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- Target Alle Transferrin Receptor (TFRC) Antikörper anzeigen
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Transferrin Receptor Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- Protein A agarose
- Immunogen
- Human myeloma cell line (RPMI8226)
- Klon
- WK7
- Isotyp
- IgG1
- Top Product
- Discover our top product TFRC Primärantikörper
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anti-Transferrin Receptor (p90, CD71) (TFRC) antibody
TFRC Reaktivität: Human FACS, IP, ICC Wirt: Maus Monoclonal MEM-75 unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 578-765) antibodyTFRC Reaktivität: Schwein WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) antibodyTFRC Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 1-140) antibodyTFRC Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) antibody (Biotin)TFRC Reaktivität: Human FACS, IP, ICC Wirt: Maus Monoclonal MEM-75 Biotin
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 649-677), (C-Term) antibodyTFRC Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal RB20736 unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 68-168) antibodyTFRC Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 1E6 unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 608-727) antibodyTFRC Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1A1B2 unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibodyTFRC Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 572-757) antibodyTFRC Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- PBS containing 1 % BSA and 0.09 % NaN3
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8 °C.
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- Target
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Andere Bezeichnung
- CD71 / TFRC (TFRC Produkte)
- Hintergrund
- CD71 is a homodimeric type II transmembrane glycoprotein consisting of two disulfide-bonded 95 kDa chains. CD71 is the transferrin receptor (TfR). The CD71 binds iron saturated holo-transferrin on the cell surface and is internalized and transported to early sorting endosomes, where the complexed iron is rapidly separated from transferrin. Subsequently, the CD71-transferrin complex accumulates within recycling endosomes and then recycles to the plasma membrane. On the cell surface, iron-free apotransferrin has negligible affinity for CD71, and is released from the cell, ready to begin a new cycle. CD 71 is expressed on activated B and T cells, macrophages, reticulocytes, erythroid precursors, and malignant tissues. Particularly high expression of CD71 is reported in the reticulocytes and erythroid series, reflecting the requirement for iron in hemoglobin. CD71 expression is upregulated on immature proliferating cells and low levels on resting mature lymphocytes. In addition to this general function, CD71 appears to play a costimulatory role in T cell activation and receptor for IgA1 antibodies.Synonyms: TfR1, Transferrin receptor protein 1, p90
- Gen-ID
- 9606
- UniProt
- P02786
- Pathways
- Transition Metal Ion Homeostasis
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