CDKN2B Antikörper

Produktnummer ABIN1449282

Produktdetails anti-CDKN2B Antikörper

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDKN2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Spezifität: This antibody reacts with p15INK4b (15 kDa).

Kreuzreaktivität (Details): Species reactivity (tested):Human (HeLa, 293T, transfectant), does not react with Mouse (NIH/3T3, P3U1) and Rat (PC12, Rat1)

Aufreinigung: Protein A agarose

Immunogen: GST-full length human p15INK4b

Klon: 1F6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Details zu CDKN2B

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Andere Bezeichnung: CDKN2B / p15INK4b (CDKN2B Produkte)

Synonyme: p14-INK4b antikoerper, cdk4l antikoerper, ink4b antikoerper, mts2 antikoerper, p15 antikoerper, p15ink4b antikoerper, tp15 antikoerper, CDK4I antikoerper, INK4B antikoerper, MTS2 antikoerper, P15 antikoerper, TP15 antikoerper, p15INK4b antikoerper, AV083695 antikoerper, INK4b antikoerper, p15(INK4b) antikoerper, CDKN2A antikoerper, cyclin dependent kinase inhibitor 2B antikoerper, Cyclin-dependent kinase 4 inhibitor B antikoerper, cyclin-dependent kinase inhibitor 2B antikoerper, cyclin-dependent kinase inhibitor 2B L homeolog antikoerper, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) antikoerper, CDKN2B antikoerper, cdn2b antikoerper, cdkn2b antikoerper, cdkn2b.L antikoerper, Cdkn2b antikoerper

Hintergrund: Progression through the G1 phase of the cell cycle is regulated in part by the D-type cyclin-dependent kinases, cdk4 and cdk6. p15INK4b is a specific inhibitor of cdk4/cdk6 and is periodically expressed during cell cycle. Induction of p15INK4b is important for TGFß-mediated cytostasis in epithelial cells but not in hematopoietic cells, it may act as an effector of TGF-ß mediated cell arrest.Synonyms: Cyclin-dependent kinase 4 inhibitor B, MTS2, Multiple tumor suppressor 2, p14-INK4b, p14INK4b, p15-INK4b

Gen-ID: 1030

NCBI Accession: NP_004927

UniProt: P42772

Pathways: Zellzyklus, Mitotic G1-G1/S Phases