CDCA8 Antikörper (N-Term)

Produktnummer ABIN1449290

Produktdetails anti-CDCA8 Antikörper

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Bindungsspezifität: AA 1-280, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDCA8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Spezifität: This antibody reacts with Borealin (35 kDa).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A agarose

Immunogen: Recombinant full-length human Borealin (1-280 aa)

Klon: 1D11

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Details zu CDCA8

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Andere Bezeichnung: CDCA8 / Borealin (CDCA8 Produkte)

Hintergrund: Borealin is a subunit of the chromosomal passenger complex (CPC), which is necessary for chromosome segregation and cytokinesis. While CPC shows a dynamic localization pattern during mitosis, Borealin and survivin, another subunit of CPC is essential to localize CPC at centromare from prophase to anaphase. It is thought that Borealin and survivin recruit aurora B, a kinase subunit of CPC, to inner centromare to allow phosphorylating appropriate substrates.Synonyms: Cell division cycle-associated protein 8, Dasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein, hDasra-B

Gen-ID: 55143

NCBI Accession: NP_060571

UniProt: Q53HL2

Pathways: Zellzyklus, M Phase