MEMO1 Antikörper (N-Term)

Produktnummer ABIN1449397

Produktdetails anti-MEMO1 Antikörper

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Bindungsspezifität: AA 1-297, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MEMO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human MEMO1 (1-297aa) purified from E. coli

Klon: AT1E9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Phosphate -Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MEMO1

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Andere Bezeichnung: MEMO1 (MEMO1 Produkte)

Synonyme: MGC89105 antikoerper, C2orf4 antikoerper, MEMO antikoerper, NS5ATP7 antikoerper, 0610016J10Rik antikoerper, D930048L02Rik antikoerper, RGD1309929 antikoerper, fi04d12 antikoerper, wu:fi04d12 antikoerper, zgc:55290 antikoerper, mediator of cell motility 1 antikoerper, mediator of cell motility 1 L homeolog antikoerper, MEMO1 antikoerper, memo1 antikoerper, Memo1 antikoerper, memo1.L antikoerper

Hintergrund: MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activitySynonyms: C21orf19-like protein, C2orf4, CGI-27, HCV NS5A-transactivated protein 7, Hepatitis C virus NS5A-transactivated protein 7, Mediator of ErbB2-driven cell motility 1, NS5ATP7

Gen-ID: 51072

NCBI Accession: NP_057039

UniProt: Q9Y316