ZNF521 Antikörper (N-Term)

Produktnummer ABIN1449926

Produktdetails anti-ZNF521 Antikörper

Target: ZNF521 (Zinc Finger Protein 521 (ZNF521))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF521 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the amino terminus of Human ZNF521

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ZNF521

Target: ZNF521 (Zinc Finger Protein 521 (ZNF521))

Andere Bezeichnung: ZNF521 (ZNF521 Produkte)

Synonyme: Znf521 antikoerper, EHZF antikoerper, Evi3 antikoerper, B930086A16Rik antikoerper, zinc finger protein 521 antikoerper, zinc finger protein 521 S homeolog antikoerper, Zfp521 antikoerper, ZNF521 antikoerper, znf521.S antikoerper

Hintergrund: The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors . ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis .Synonyms: EHZF, Early hematopoietic zinc finger protein, LIP3, LYST-interacting protein 3, Zinc finger protein 521

Gen-ID: 25925

NCBI Accession: NP_056276