cb212 antikoerper, prc1 antikoerper, prc1l antikoerper, zgc:55982 antikoerper, zgc:86918 antikoerper, MGC68845 antikoerper, zgc:55664 antikoerper, ase1 antikoerper, ASE1 antikoerper, D7Ertd348e antikoerper, protein regulator of cytokinesis 1 antikoerper, protein regulator of cytokinesis 1a antikoerper, protein regulator of cytokinesis 1 S homeolog antikoerper, protein regulator of cytokinesis 1b antikoerper, PRC1 antikoerper, prc1a antikoerper, prc1.S antikoerper, prc1b antikoerper, CNC07120 antikoerper, prc1 antikoerper, Prc1 antikoerper
Hintergrund
PRC1 (Protein Regulator of Cytokinesis 1) is a key regulator of cytokinesis and has been identified as a substrate for several cyclin-dependent kinases (CDKs). High levels of PRC1 expression occurs during S and G2/M and drops dramatically after mitosis exit and G1 entry. It is located in the nucleus during interphase and binds to the midzone of mitotic spindles during anaphase and is localized to the cell midbody during cytokinesis. Depletion of PRC1 has been shown to prevent cellular cleavage, but it has no effect on nuclear division, demonstrating the importance of PRC1 in mitosis.Synonyms: ASE1, Protein regulator of cytokinesis 1