DELE1/KIAA0141 Antikörper (N-Term)

Produktnummer ABIN1449949

Produktdetails anti-DELE1/KIAA0141 Antikörper

Target: DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DELE1/KIAA0141 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the amino terminus of Human DELE

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DELE1/KIAA0141

Target: DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

Andere Bezeichnung: KIAA0141 (DELE1 Produkte)

Synonyme: KIAA0141 antikoerper, MGC139304 antikoerper, DELE antikoerper, 2700004E22Rik antikoerper, Dele antikoerper, Kiaa0141 antikoerper, KIAA0141 antikoerper, KIAA0141 ortholog antikoerper, RIKEN cDNA 0610009O20 gene antikoerper, SEL1 domain containing protein RGD735029 antikoerper, KIAA0141 antikoerper, 0610009O20Rik antikoerper, RGD735029 antikoerper

Hintergrund: DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-alpha and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-alpha, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.

Gen-ID: 9812

NCBI Accession: NP_055588