RUTBC2 antikoerper, 2410098H20Rik antikoerper, AA408781 antikoerper, D5Bwg1524e antikoerper, E130107M15 antikoerper, NuIP antikoerper, Rutbc2 antikoerper, small G protein signaling modulator 1 antikoerper, SGSM1 antikoerper, Sgsm1 antikoerper
Hintergrund
Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.Synonyms: RUTBC2, Small G protein signaling modulator 1