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FAM193B Antikörper (N-Term)

FAM193B Reaktivität: Human WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1450012
  • Target Alle FAM193B Produkte
    FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
    Bindungsspezifität
    • 2
    • 1
    N-Term
    Reaktivität
    Human
    Wirt
    • 2
    Kaninchen
    Klonalität
    • 2
    Polyklonal
    Konjugat
    • 2
    Dieser FAM193B Antikörper ist unkonjugiert
    Applikation
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    16 amino acid synthetic peptide near the amino terminus of Human FAM193B
    Isotyp
    IgG
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
    Andere Bezeichnung
    FAM193B (FAM193B Produkte)
    Synonyme
    IRIZIO antikoerper, Kiaa1931 antikoerper, family with sequence similarity 193 member B antikoerper, family with sequence similarity 193, member B antikoerper, FAM193B antikoerper, Fam193b antikoerper
    Hintergrund
    FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.Synonyms: Family with sequence similarity 193 member B, IRIZIO
    Molekulargewicht
    99 kDa
    Gen-ID
    54540
    UniProt
    Q96PV7
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