KCNK12 Antikörper (C-Term)

Produktnummer ABIN1450041

Produktdetails anti-KCNK12 Antikörper

Target: KCNK12 (Potassium Channel, Subfamily K, Member 12 (KCNK12))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNK12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid synthetic peptide near the carboxy terminus of Human KCNK12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KCNK12

Target: KCNK12 (Potassium Channel, Subfamily K, Member 12 (KCNK12))

Andere Bezeichnung: KCNK12 (KCNK12 Produkte)

Synonyme: KCNK12 antikoerper, K2p12.1 antikoerper, THIK-2 antikoerper, THIK2 antikoerper, mntk1 antikoerper, potassium two pore domain channel subfamily K member 12 antikoerper, potassium channel, subfamily K, member 12 antikoerper, KCNK12 antikoerper, Kcnk12 antikoerper

Hintergrund: KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle. KCNK12 is closely related to KCNK13 (58 % identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.Synonyms: KCNK12, Potassium channel subfamily K member 12, THIK-2, Tandem pore domain halothane-inhibited potassium channel 2

Gen-ID: 56660

NCBI Accession: NP_071338