SEC62 Antikörper (C-Term)

Produktnummer ABIN1450053

Produktdetails anti-SEC62 Antikörper

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEC62 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the carboxy terminus of Human SEC62

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SEC62

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Andere Bezeichnung: SEC62 / TLOC1 (TLOC1 Produkte)

Synonyme: tloc1 antikoerper, TLOC1 antikoerper, wu:fb57b06 antikoerper, zgc:114073 antikoerper, Dtrp1 antikoerper, HTP1 antikoerper, TP-1 antikoerper, 3100002M17Rik antikoerper, AI844545 antikoerper, AW545092 antikoerper, Tloc1 antikoerper, Ab2-292 antikoerper, SEC62 homolog, preprotein translocation factor S homeolog antikoerper, SEC62 homolog, preprotein translocation factor antikoerper, membrane unit of ER protein translocation apparatus antikoerper, SEC62 homolog (S. cerevisiae) antikoerper, sec62.S antikoerper, SEC62 antikoerper, sec62 antikoerper, Sec62 antikoerper

Hintergrund: SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane. It is speculated that SEC61-SEC62-SEC63 may perform post-translational protein translocation into the ER and might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Silencing of this gene with RNAi dramatically reduced the migration and invasive potential of numerous tumor cell lines, suggesting that it may be an attractive target for therapy of various tumors.Synonyms: Translocation protein 1, Translocation protein SEC62

Gen-ID: 7095

NCBI Accession: NP_003253