PRICKLE2 Antikörper (Middle Region)
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- Target Alle PRICKLE2 Antikörper anzeigen
- PRICKLE2 (Prickle Homolog 2 (PRICKLE2))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PRICKLE2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse, Rat.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 15 amino acid synthetic peptide near the center of human PRICKLE2
- Isotyp
- IgG
- Top Product
- Discover our top product PRICKLE2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- PRICKLE2 (Prickle Homolog 2 (PRICKLE2))
- Andere Bezeichnung
- PRICKLE2 (PRICKLE2 Produkte)
- Synonyme
- EPM5 antikoerper, 6230400G14Rik antikoerper, 6720451F06Rik antikoerper, mpk2 antikoerper, cb886 antikoerper, im:7138215 antikoerper, pk2 antikoerper, prickle planar cell polarity protein 2 antikoerper, prickle homolog 2b antikoerper, PRICKLE2 antikoerper, Prickle2 antikoerper, prickle2b antikoerper
- Hintergrund
- PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity. Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth, and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells. PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors. Defects in the gene encoding PRICKLE2 are associated with autosomal recessive progressive myoclonic epilepsy.Synonyms: PRICKLE-2, Prickle-like protein 2
- Gen-ID
- 166336
- NCBI Accession
- NP_942559
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