AFAP Antikörper (N-Term)
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- Target Alle AFAP (AFAP1) Antikörper anzeigen
- AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AFAP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- AFAP1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of Human AFAP1
- Isotyp
- IgG
- Top Product
- Discover our top product AFAP1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))
- Andere Bezeichnung
- AFAP1 (AFAP1 Produkte)
- Synonyme
- afap antikoerper, afap-110 antikoerper, AFAP antikoerper, AFAP-110 antikoerper, AFAP110 antikoerper, 2600003E23Rik antikoerper, 9630044L16Rik antikoerper, AI848729 antikoerper, Afap antikoerper, mKIAA3018 antikoerper, actin filament associated protein 1 antikoerper, AFAP1 antikoerper, afap1 antikoerper, Afap1 antikoerper
- Hintergrund
- The actin filament-associated protein AFAP1 (AFAP-110) is an actin cross-linking protein first identified as a substrate of the viral oncogene v-Src. AFAP1 has a fundamental role in actin cytoskeleton arrangement. It contains a carboxyterminal actin-binding domain that directly binds to F-actin and serves as an adaptor protein in the regulation of SRC and PKC signal transduction by several functional domains, including 2 pleckstrin homology (PH) domains, a Src homology 3-binding (SH3-binding) motif, and several SH2-binding motifs. It is overexpressed in prostate carcinoma and contributes to tumor growth by regulating cell-matrix adhesions and migration in the cancer cells. AFAP1 represent a possible therapeutic target for controlling tumorigenesis and metastasis.Synonyms: 110 kDa actin filament-associated protein, AFAP-110, Actin filament-associated protein 1
- Gen-ID
- 60312
- NCBI Accession
- NP_940997
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