SIRT1 Antikörper (AA 577-590)
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- Target Alle SIRT1 Antikörper anzeigen
- SIRT1 (Sirtuin 1 (SIRT1))
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Bindungsspezifität
- AA 577-590
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Reaktivität
- Human, Affe
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser SIRT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Marke
- IHC-plus™
- Spezifität
- Human SIRT1. This antibody is expected to recognize both reported isoforms (NP_036370.2, NP_001135970.1).
- Homologie
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Mouse (93%) Rat (86%).
- Aufreinigung
- Immunoaffinity purified
- Immunogen
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Synthetic peptide C-EKPQEVQTSRNVES from an internal region of human SIRT1 (NP_036370.2, NP_001135970.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Mouse (93%), Rat (86%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product SIRT1 Primärantikörper
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- Applikationshinweise
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Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:64000), WB (0.05 - 0.2 μg/mL)
Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 120kD band observed in lysates of cell line Jurkat (calculated MW of 81.7kD according to NP_036370.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Cheng et al, Proc Natl Acad Sci U S A. 2003 Sep 16,100(19):10794-9., PMID: 12960381). Recommended concentration: 0.05-0.2 μg/mL. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Minimize freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- SIRT1 (Sirtuin 1 (SIRT1))
- Andere Bezeichnung
- SIRT1 / Sirtuin 1 (SIRT1 Produkte)
- Synonyme
- sirtuin 1 antikoerper, AA673258 antikoerper, SIR2L1 antikoerper, Sir2 antikoerper, Sir2a antikoerper, Sir2alpha antikoerper, sir2l1 antikoerper, sirtuin antikoerper, SIR2 antikoerper, sirtuin 1 antikoerper, sirtuin 1 L homeolog antikoerper, SIRT1 antikoerper, SRT1 antikoerper, Sirt1 antikoerper, sirt1.L antikoerper
- Hintergrund
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Name/Gene ID: SIRT1
Family: ADP-Ribosyltransferase
Synonyms: SIRT1, SIR2-like protein 1, SIR2alpha, SIR2L1, Sirtuin 1, Sir2-like 1, Sirtuin type 1, HSIR2, HSIRT1 - Gen-ID
- 23411
- NCBI Accession
- NP_036370, NP_001135970
- UniProt
- Q96EB6
- Pathways
- MAPK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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