RAGE Antikörper (AA 30-330)

Produktnummer ABIN1512545

Produktdetails anti-RAGE Antikörper

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Bindungsspezifität: AA 30-330

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAGE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IGEPLVLKCK GAPKKPPQRL EWKLNTGRTE AWKVLSPQGG GPWDSVARVL PNGSLFLPAV GIQDEGIFRC QAMNRNGKET KSNYRVRVYQ IPGKPEIVDS ASELTAGVPN KVGTCVSEGS YPAGTLSWHL DGKPLVPNEK GVSVKEQTRR HPETGLFTLQ SELMVTPARG GDPRPTFSCS FSPGLPRHRA LRTAPIQPRV WEPVPLEEVQ LVVEPEGGAV APGGTVTLTC EVPAQPSPQI HWMKDGVPLP LPPSPVLILP EIGPQDQGTY SCVATHSSHG PQESRAVSIS IIEPGEEGPT A

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-330 of human AGER (NP_001127.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RAGE

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Andere Bezeichnung: AGER (AGER Produkte)

Hintergrund: The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).,AGER,RAGE,SCARJ1,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,AGER

Molekulargewicht: 13 kDa/35-44 kDa

Gen-ID: 177

UniProt: Q15109

Pathways: Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteine