ERCC5 Antikörper (AA 1-270)

Produktnummer ABIN1512873

Produktdetails anti-ERCC5 Antikörper

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Bindungsspezifität: AA 1-270

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERCC5 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Sequenz: MGVQGLWKLL ECSGRQVSPE ALEGKILAVD ISIWLNQALK GVRDRHGNSI ENPHLLTLFH RLCKLLFFRI RPIFVFDGDA PLLKKQTLVK RRQRKDLASS DSRKTTEKLL KTFLKRQAIK TAFRSKRDEA LPSLTQVRRE NDLYVLPPLQ EEEKHSSEEE DEKEWQERMN QKQALQEEFF HNPQAIDIES EDFSSLPPEV KHEILTDMKE FTKRRRTLFE AMPEESDDFS QYQLKGLLKK NYLNQHIEHV QKEMNQQHSG HIRRQYEDEG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ERCC5 (NP_000114.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ERCC5

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Andere Bezeichnung: ERCC5 (ERCC5 Produkte)

Synonyme: COFS3 antikoerper, ERCM2 antikoerper, UVDR antikoerper, XPG antikoerper, XPGC antikoerper, cofs3 antikoerper, ercm2 antikoerper, uvdr antikoerper, xpg antikoerper, xpgc antikoerper, Xpg antikoerper, ERCC excision repair 5, endonuclease antikoerper, excision repair cross-complementation group 5 L homeolog antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 5 antikoerper, ERCC5 antikoerper, ercc5.L antikoerper, Ercc5 antikoerper

Hintergrund: This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.,ERCC5,COFS3,ERCC5-201,ERCM2,UVDR,XPG,XPGC,Epigenetics & Nuclear Signaling,DNA Damage & Repair,ERCC5

Molekulargewicht: 27 kDa/47 kDa/133 kDa

Gen-ID: 2073

UniProt: P28715

Pathways: DNA Reparatur