NeuN Antikörper (AA 1-220)

Produktnummer ABIN1513254

Produktdetails anti-NeuN Antikörper

Target: NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))

Bindungsspezifität: AA 1-220

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NeuN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MAQPYPPAQY PPPPQNGIPA EYAPPPPHPT QDYSGQTPVP TEHGMTLYTP AQTHPEQPGS EASTQPIAGT QTVPQTDEAA QTDSQPLHPS DPTEKQQPKR LHVSNIPFRF RDPDLRQMFG QFGKILDVEI IFNERGSKGF GFVTFETSSD ADRAREKLNG TIVEGRKIEV NNATARVMTN KKTGNPYTNG WKLNPVVGAV YGPEFYAVTG FPYPTTGTAV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NeuN (NP_001076044.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-NeuN Antikörper (ABIN1513254)

Liu, Qin, Dai, Zhang, Xue, Ni, Han, Zhu, Yuan, Tao, Cao: "SMAD4 is Involved in the Development of Endotoxin Tolerance in Microglia." in: Cellular and molecular neurobiology, Vol. 36, Issue 5, pp. 777-88, (2017) (PubMed).

Details zu NeuN

Target: NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))

Andere Bezeichnung: RBFOX3 (RBFOX3 Produkte)

Synonyme: FOX-3 antikoerper, FOX3 antikoerper, HRNBP3 antikoerper, NEUN antikoerper, Fox-3 antikoerper, Hrnbp3 antikoerper, NeuN antikoerper, Neuna60 antikoerper, Neun antikoerper, RGD1560070 antikoerper, RNA binding fox-1 homolog 3 antikoerper, RNA binding protein, fox-1 homolog (C. elegans) 3 antikoerper, RNA binding protein, fox-1 homolog 3 antikoerper, RBFOX3 antikoerper, Rbfox3 antikoerper

Hintergrund: This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.,FOX-3,FOX3,HRNBP3,NEUN,NeuN,RBFOX3,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,Cell Type Marker,Neuron marker,RBFOX3

Molekulargewicht: 33 kDa/35 kDa

Gen-ID: 146713

UniProt: A6NFN3