IKK-alpha /IKK-beta Antikörper (pSer180)
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- Target Alle IKK-alpha /IKK-beta Produkte
- IKK-alpha /IKK-beta
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Bindungsspezifität
- AA 151-200, pSer180
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Reaktivität
- Maus, Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IKK-alpha /IKK-beta Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
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IKK-alpha/beta (Phospho-Ser180/181) Antibody detects endogenous levels of IKK-alpha/beta only when phosphorylated at Ser180/181.
PhosphorylationH:S180/S181 M:S180/S181 R:S180/S181
- Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- Reinheit
- > 95 %
- Immunogen
- The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta around the phosphorylation site of Ser180/181.
- Isotyp
- IgG
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- Applikationshinweise
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
- Kommentare
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Unigene-Number: Hs.198998, Hs.656458 (NCBI Gene Symbol: CHUK)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
- Haltbarkeit
- 12 months
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PMC, a potent hydrophilic ?-tocopherol derivative, inhibits NF-?B activation via PP2A but not I?B?-dependent signals in vascular smooth muscle cells." in: Journal of cellular and molecular medicine, Vol. 18, Issue 7, pp. 1278-89, (2014) (PubMed).
: "
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PMC, a potent hydrophilic ?-tocopherol derivative, inhibits NF-?B activation via PP2A but not I?B?-dependent signals in vascular smooth muscle cells." in: Journal of cellular and molecular medicine, Vol. 18, Issue 7, pp. 1278-89, (2014) (PubMed).
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- Target
- IKK-alpha /IKK-beta
- Andere Bezeichnung
- IKK-alpha/beta (IKK-alpha /IKK-beta Produkte)
- Hintergrund
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Synonyms: CHUK, Conserved helix-loop-helix ubiquitous kinase, I kappa-B kinase alpha, I-kappa-B kinase 1, IkappaB kinase, IkBKA, IKK-A, IKK-alpha, IKK1, IKKA, Inhibitor of nuclear factor kappa-B kinase alpha subunit, kinase IKK-alpha, NFKBIKA, Nuclear factor NFkapp
NCBI Gene Symbol: CHUK
- Molekulargewicht
- 84 kDa
- Gen-ID
- 1147, 3551
- OMIM
- 600664
- UniProt
- O15111, O14920
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