NCF1 Antikörper (pSer328)

Produktnummer ABIN1531718

Produktdetails anti-NCF1 Antikörper

Target: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Bindungsspezifität: AA 301-350, pSer328

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCF1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Spezifität:

Neutrophil Cytosol Factor 1 (Phospho-Ser328) Antibody detects endogenous levels of Neutrophil Cytosol Factor 1 only when phosphorylated at Ser328.

PhosphorylationH:S328 M:S329 R:S329

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Neutrophil Cytosol Factor 1 around the phosphorylation site of Ser328.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC: 1:50~1:100 ELISA: 1:1000

Kommentare:

Unigene-Number: Hs.647047, Hs.655201 (NCBI Gene Symbol: NCF1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Referenzen für anti-NCF1 Antikörper (ABIN1531718)

Kröller-Schön, Steven, Kossmann, Scholz, Daub, Oelze, Xia, Hausding, Mikhed, Zinßius, Mader, Stamm, Treiber, Scharffetter-Kochanek, Li, Schulz, Wenzel, Münzel, Daiber: "Molecular mechanisms of the crosstalk between mitochondria and NADPH oxidase through reactive oxygen species - studies in white blood cells and in animal models." in: Antioxidants & redox signaling, (2013) (PubMed).

Details zu NCF1

Target: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Andere Bezeichnung: Neutrophil Cytosol Factor 1 (NCF1 Produkte)

Hintergrund:

Synonyms: 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-1, NCF-47K, NCF1, Neutrophil cytosol factor 1, Neutrophil cytosolic factor 1, Neutrophil NADPH oxidase factor 1, P47 phox, p47-phox

NCBI Gene Symbol: NCF1

Molekulargewicht: 44 kDa

Gen-ID: 653361

OMIM: 233700

UniProt: P14598

Pathways: PI3K-Akt Signalweg