Caspase 8 Antikörper (pTyr380)
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- Target Alle Caspase 8 (CASP8) Antikörper anzeigen
- Caspase 8 (CASP8)
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Bindungsspezifität
- AA 346-395, pTyr380
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caspase 8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
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Caspase 8 (Phospho-Tyr380) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Tyr380.
PhosphorylationH:Y380
- Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- Reinheit
- > 95 %
- Immunogen
- The antiserum was produced against synthesized peptide derived from human Caspase 8 around the phosphorylation site of Tyr380.
- Isotyp
- IgG
- Top Product
- Discover our top product CASP8 Primärantikörper
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- Applikationshinweise
- WB: 1:500~1:1000 ELISA: 1:10000
- Kommentare
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Unigene-Number: Hs.599762 (NCBI Gene Symbol: CASP8)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
- Haltbarkeit
- 12 months
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Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33263-71, (2013) (PubMed).
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Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33263-71, (2013) (PubMed).
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- Target
- Caspase 8 (CASP8)
- Andere Bezeichnung
- Caspase 8 (CASP8 Produkte)
- Hintergrund
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Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog
NCBI Gene Symbol: CASP8
- Molekulargewicht
- 55 kDa
- Gen-ID
- 841
- OMIM
- 211980
- UniProt
- Q14790
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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