TGFB1 Antikörper (AA 336-385)

Produktnummer ABIN1533412

Produktdetails anti-TGFB1 Antikörper

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Bindungsspezifität: AA 336-385

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TGFB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität:

TGF beta1 Antibody detects endogenous levels of total TGF beta1 protein.

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TGF beta1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000

Kommentare:

Unigene-Number: Hs.645227 (NCBI Gene Symbol: TGFB1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Referenzen für anti-TGFB1 Antikörper (ABIN1533412)

Matsumoto, Niimi, Kohyama: "Characterization of fibrosis-promoting factors and siRNA-mediated therapies in C-protein-induced experimental autoimmune myocarditis." in: Cellular immunology, Vol. 279, Issue 1, pp. 70-7, (2012) (PubMed).

Details zu TGFB1

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Andere Bezeichnung: TGF Beta1 (TGFB1 Produkte)

Hintergrund:

Synonyms: CED, diaphyseal dysplasia 1, progressive, DPD1, TGF-beta 1, TGFB, transforming growth factor, beta 1, transforming growth factor, beta 1 (Camurati-Engelmann disease)

NCBI Gene Symbol: TGFB1

Molekulargewicht: 44 kDa

Gen-ID: 7040

OMIM: 131300

UniProt: P01137

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie, Cancer Immune Checkpoints