This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the C-terminal region of human GP9.
cd42a antikoerper, gpix antikoerper, GP9 antikoerper, GPIX antikoerper, Cd42 antikoerper, CD42a antikoerper, glycoprotein IX platelet antikoerper, glycoprotein IX platelet L homeolog antikoerper, glycoprotein IX (platelet) antikoerper, glycoprotein 9 (platelet) antikoerper, GP9 antikoerper, gp9.L antikoerper, Gp9 antikoerper
Hintergrund
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq].