Kallikrein 2 Antikörper (C-Term)

Produktnummer ABIN1536788

Produktdetails anti-Kallikrein 2 Antikörper

Target: Kallikrein 2 (KLK2)

Bindungsspezifität: AA 166-197, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Kallikrein 2 (KLK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the C-terminal region of human Kallikrein 2 (KLK2).

Klon: RB06101

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Kallikrein 2 Antikörper (ABIN1536788)

Guihard, Yao, Blazquez-Medela, Iruela-Arispe, Boström, Yao: "Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice." in: PLoS ONE, Vol. 11, Issue 12, pp. e0167936, (2017) (PubMed).

Details zu Kallikrein 2

Target: Kallikrein 2 (KLK2)

Abstract: KLK2 Produkte

Hintergrund: Kallikreins are a group of serine proteases manifesting diverse physiological functions. The glandular kallikreins are a distinct group of serine proteases with an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Many kallikrein genes are differentially expressed in various malignancies. Human glandular kallikrein (hK2, encoded by the KLK2 gene) is an emerging tumor marker for prostate cancer.

Molekulargewicht: 28671

Gen-ID: 3817

NCBI Accession: NP_001002231, NP_001243009, NP_005542

UniProt: P20151

Pathways: Komplementsystem