This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CHMP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-204 amino acids from the C-terminal region of human CHMP5.
SNF7DC2 antikoerper, cgi-34 antikoerper, hspc177 antikoerper, pnas-2 antikoerper, vps60 antikoerper, chmp5 antikoerper, zgc:64125 antikoerper, C9orf83 antikoerper, HSPC177 antikoerper, PNAS-2 antikoerper, Vps60 antikoerper, 2210412K09Rik antikoerper, AW545668 antikoerper, RGD1305968 antikoerper, charged multivesicular body protein 5 S homeolog antikoerper, charged multivesicular body protein 5b antikoerper, charged multivesicular body protein 5 antikoerper, charged multivesicular body protein 5 L homeolog antikoerper, chromatin modifying protein 5 antikoerper, chmp5.S antikoerper, chmp5b antikoerper, CHMP5 antikoerper, chmp5.L antikoerper, chmp5 antikoerper, Chmp5 antikoerper
Hintergrund
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).