HUS1 Antikörper (C-Term)

Produktnummer ABIN1536829

Produktdetails anti-HUS1 Antikörper

Target: HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

Bindungsspezifität: AA 199-226, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HUS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HUS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-226 amino acids from the C-terminal region of human HUS1.

Klon: RB36257

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: HUS1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu HUS1

Target: HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

Andere Bezeichnung: HUS1 (HUS1 Produkte)

Synonyme: hHUS1 antikoerper, mHus1 antikoerper, XHus1 antikoerper, hus1 antikoerper, HUS1 checkpoint clamp component antikoerper, checkpoint clamp complex protein Hus1 antikoerper, HUS1 checkpoint clamp component L homeolog antikoerper, HUS1 antikoerper, Hus1 antikoerper, hus1 antikoerper, hus1.L antikoerper

Hintergrund: The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. [provided by RefSeq].

Molekulargewicht: 31691

Gen-ID: 3364

NCBI Accession: NP_004498

UniProt: O60921