This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the C-terminal region of human TEF.
2310028D20Rik antikoerper, tef antikoerper, tefb antikoerper, tefbeta antikoerper, wu:fa12f02 antikoerper, wu:fb11h02 antikoerper, zTEF[a] antikoerper, VBP antikoerper, xtef antikoerper, TEF antikoerper, DKFZp459A027 antikoerper, dbp antikoerper, TEF2 antikoerper, zgc:112180 antikoerper, TEF, PAR bZIP transcription factor antikoerper, thyrotroph embryonic factor antikoerper, thyrotrophic embryonic factor a antikoerper, thyrotrophic embryonic factor antikoerper, D site of albumin promoter (albumin D-box) binding protein L homeolog antikoerper, thyrotrophic embryonic factor b antikoerper, TEF antikoerper, Tef antikoerper, tefa antikoerper, tef antikoerper, dbp.L antikoerper, tefb antikoerper
Hintergrund
Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP), VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].