Septin 2 Antikörper (C-Term)

Produktnummer ABIN1537024

Produktdetails anti-Septin 2 Antikörper

Target: Septin 2 (SEPT2)

Bindungsspezifität: AA 280-309, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human SEPT2.

Klon: RB36619

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: SEPT2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu Septin 2

Target: Septin 2 (SEPT2)

Andere Bezeichnung: SEPT2 (SEPT2 Produkte)

Synonyme: DIFF6 antikoerper, NEDD5 antikoerper, Pnutl3 antikoerper, hNedd5 antikoerper, AW208991 antikoerper, Nedd-5 antikoerper, Nedd5 antikoerper, mKIAA0158 antikoerper, Vesp11 antikoerper, nedd5 antikoerper, wu:fb52g01 antikoerper, wu:fb99a01 antikoerper, Septin-2A antikoerper, Septin-A antikoerper, diff6 antikoerper, pnutl3 antikoerper, sept2 antikoerper, septa antikoerper, xlsepta antikoerper, SEPT2 antikoerper, Sep-02 antikoerper, Septin-2B antikoerper, hnedd5 antikoerper, sept2-B antikoerper, Septin-2 antikoerper, septin 2 antikoerper, septin 2 L homeolog antikoerper, septin 2-like antikoerper, COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain antikoerper, septin 2 S homeolog antikoerper, SEPT2 antikoerper, Sept2 antikoerper, sept2 antikoerper, sept2.L antikoerper, SEPT2L antikoerper, sepT2 antikoerper, sept2.S antikoerper

Hintergrund: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Molekulargewicht: 41487

Gen-ID: 4735

NCBI Accession: NP_001008491, NP_001008492, NP_004395, NP_006146

UniProt: Q15019