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FBXL19 Antikörper (C-Term)

FBXL19 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB38770 unconjugated
Produktnummer ABIN1537454
  • Target Alle FBXL19 Antikörper anzeigen
    FBXL19 (F-Box and Leucine-Rich Repeat Protein 19 (FBXL19))
    Bindungsspezifität
    • 9
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    AA 543-570, C-Term
    Reaktivität
    • 24
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 23
    • 1
    Kaninchen
    Klonalität
    • 23
    • 1
    Polyklonal
    Konjugat
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser FBXL19 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 17
    • 2
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This FBXL19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-570 amino acids from the C-terminal region of human FBXL19.
    Klon
    RB38770
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product FBXL19 Primärantikörper
  • Applikationshinweise
    WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    FBXL19 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Dong, Zhao, Wei, Bowser, Khoo, Liu, Luketich, Pennathur, Ma, Zhao: "F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation." in: Molecular cancer, Vol. 13, pp. 76, (2014) (PubMed).

    Wei, Mialki, Dong, Khoo, Mallampalli, Zhao, Zhao: "A new mechanism of RhoA ubiquitination and degradation: Roles of SCF(FBXL19) E3 ligase and Erk2." in: Biochimica et biophysica acta, (2013) (PubMed).

    Zhao, Mialki, Wei, Coon, Zou, Chen, Mallampalli, Zhao: "SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 7, pp. 2611-9, (2013) (PubMed).

  • Target
    FBXL19 (F-Box and Leucine-Rich Repeat Protein 19 (FBXL19))
    Andere Bezeichnung
    FBXL19 (FBXL19 Produkte)
    Synonyme
    Fbl19 antikoerper, JHDM1C antikoerper, 6030430O11 antikoerper, BC059812 antikoerper, F-box and leucine rich repeat protein 19 antikoerper, F-box and leucine-rich repeat protein 19 antikoerper, F-box and leucine-rich repeat protein 19 S homeolog antikoerper, F-box/LRR-repeat protein 19 antikoerper, FBXL19 antikoerper, Fbxl19 antikoerper, fbxl19.S antikoerper, LOC540981 antikoerper, LOC100431704 antikoerper
    Hintergrund
    Members of the F-box protein family, such as FBXL19, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
    Molekulargewicht
    75707
    Gen-ID
    54620
    NCBI Accession
    NP_001093254, NP_001269280
    UniProt
    Q6PCT2
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