This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This Mouse Shb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-95 amino acids from the C-terminal region of mouse Shb.
SHB antikoerper, RP11-3J10.8 antikoerper, bA3J10.2 antikoerper, RGD1565350 antikoerper, BC028832 antikoerper, SH2 domain containing adaptor protein B antikoerper, src homology 2 domain-containing transforming protein B antikoerper, SHB antikoerper, Shb antikoerper
Hintergrund
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells (By similarity).