Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

RAD50 Antikörper (C-Term)

RAD50 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB40014 unconjugated
Produktnummer ABIN1537647
  • Target Alle RAD50 Antikörper anzeigen
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    Bindungsspezifität
    • 16
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 911-938, C-Term
    Reaktivität
    • 56
    • 50
    • 18
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 65
    • 6
    Kaninchen
    Klonalität
    • 64
    • 7
    Polyklonal
    Konjugat
    • 35
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RAD50 Antikörper ist unkonjugiert
    Applikation
    • 60
    • 24
    • 16
    • 16
    • 13
    • 13
    • 10
    • 10
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Rad50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-938 amino acids from the C-terminal region of mouse Rad50.
    Klon
    RB40014
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product RAD50 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Mouse Rad50 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    Andere Bezeichnung
    Rad50 (RAD50 Produkte)
    Synonyme
    NBSLD antikoerper, RAD502 antikoerper, hRad50 antikoerper, Mrell antikoerper, Rad50l antikoerper, 6339 antikoerper, CG6339 antikoerper, Dmel\\CG6339 antikoerper, Dmrad50 antikoerper, RAD50 antikoerper, Rad50 antikoerper, ATRAD50 antikoerper, DNA REPAIR-RECOMBINATION PROTEIN antikoerper, F22D22.28 antikoerper, F22D22_28 antikoerper, SPAP4C9.01c antikoerper, im:6906849 antikoerper, si:ch211-79h18.3 antikoerper, RAD50 double strand break repair protein antikoerper, CG6339 gene product from transcript CG6339-RE antikoerper, RAD50 homolog, double strand break repair protein L homeolog antikoerper, rad50 antikoerper, DNA repair protein RAD50 antikoerper, RAD50 homolog, double strand break repair protein antikoerper, DNA repair-recombination protein (RAD50) antikoerper, MRX complex DNA-binding subunit antikoerper, DNA repair protein Rad50 antikoerper, RAD50 recombination protein antikoerper, Rad50 DNA repair/recombination protein antikoerper, DNA repair protein rad-50 antikoerper, RAD50 antikoerper, Rad50 antikoerper, rad50 antikoerper, rad50.L antikoerper, LOC658288 antikoerper, LOC726642 antikoerper, rad-50 antikoerper
    Hintergrund
    Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation (By similarity).
    Molekulargewicht
    153488
    Gen-ID
    19360
    UniProt
    P70388
    Pathways
    DNA Reparatur, Protein targeting to Nucleus
Sie sind hier:
Kundenservice