This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CYLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-940 amino acids from the C-terminal region of human CYLN2.
The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.