NOTCH3 Antikörper (C-Term)

Produktnummer ABIN1537680

Produktdetails anti-NOTCH3 Antikörper

Target: NOTCH3 (Notch 3 (NOTCH3))

Bindungsspezifität: AA 2291-2321, C-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NOTCH3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This NOTCH3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 2291-2321 amino acids from the C-terminal region of human NOTCH3.

Klon: 487CT6-9-2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:100~250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: NOTCH3 Antibody (C-term Q2306) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu NOTCH3

Target: NOTCH3 (Notch 3 (NOTCH3))

Andere Bezeichnung: NOTCH3 (NOTCH3 Produkte)

Synonyme: CADASIL antikoerper, CASIL antikoerper, IMF2 antikoerper, AW229011 antikoerper, N3 antikoerper, hpbk antikoerper, fa14b08 antikoerper, notch5 antikoerper, wu:fa14b08 antikoerper, notch 3 antikoerper, NOTCH3 antikoerper, Notch3 antikoerper, notch3 antikoerper

Hintergrund: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq].

Molekulargewicht: 243631

Gen-ID: 4854

NCBI Accession: NP_000426

UniProt: Q9UM47

Pathways: Notch Signalweg