MLH1 Antikörper (AA 458-489)
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- Target Alle MLH1 Antikörper anzeigen
- MLH1 (MutL Homolog 1 (MLH1))
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Bindungsspezifität
- AA 458-489
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MLH1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
- Immunogen
- This MLH1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 458-489 amino acids from the Central region of human MLH1.
- Klon
- 628CT4-6-1
- Isotyp
- IgG1
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- Applikationshinweise
- WB: 1:100~400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- MLH1 Antibody (Center)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- MLH1 (MutL Homolog 1 (MLH1))
- Andere Bezeichnung
- MLH1 (MLH1 Produkte)
- Hintergrund
- This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
- Molekulargewicht
- 84601
- Gen-ID
- 4292
- NCBI Accession
- NP_000240, NP_001161089, NP_001161090, NP_001161091, NP_001245200, NP_001245202, NP_001245203
- UniProt
- P40692
- Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
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