PPIL5 Antikörper (AA 127-153)

Produktnummer ABIN1537806

Produktdetails anti-PPIL5 Antikörper

Target: PPIL5 (LRR1) (Leucine Rich Repeat Protein 1 (LRR1))

Bindungsspezifität: AA 127-153

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPIL5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPIL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-153 amino acids from the Central region of human PPIL5.

Klon: RB38338

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PPIL5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu PPIL5

Target: PPIL5 (LRR1) (Leucine Rich Repeat Protein 1 (LRR1))

Andere Bezeichnung: PPIL5 (LRR1 Produkte)

Synonyme: 2410005L11Rik antikoerper, AU021780 antikoerper, LRR-1 antikoerper, Ppil5 antikoerper, 4-1BBLRR antikoerper, PPIL5 antikoerper, leucine rich repeat protein 1 antikoerper, Lrr1 antikoerper, LRR1 antikoerper

Hintergrund: The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Molekulargewicht: 46723

Gen-ID: 122769

NCBI Accession: NP_689542, NP_982292

UniProt: Q96L50