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NARF Antikörper (AA 134-160)

NARF Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB37217 unconjugated
Produktnummer ABIN1537831
  • Target Alle NARF Antikörper anzeigen
    NARF (Nuclear Prelamin A Recognition Factor (NARF))
    Bindungsspezifität
    • 16
    • 7
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 134-160
    Reaktivität
    • 35
    • 20
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 50
    • 1
    Kaninchen
    Klonalität
    • 50
    • 1
    Polyklonal
    Konjugat
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NARF Antikörper ist unkonjugiert
    Applikation
    • 39
    • 27
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This NARF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-160 amino acids from the Central region of human NARF.
    Klon
    RB37217
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NARF Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    NARF Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    NARF (Nuclear Prelamin A Recognition Factor (NARF))
    Andere Bezeichnung
    NARF (NARF Produkte)
    Synonyme
    NARF antikoerper, IOP2 antikoerper, 4430402O11Rik antikoerper, RGD1310894 antikoerper, wu:fa03c01 antikoerper, zgc:92186 antikoerper, nuclear prelamin A recognition factor antikoerper, nuclear prelamin A recognition factor L homeolog antikoerper, NARF antikoerper, NAEGRDRAFT_78871 antikoerper, VDBG_04882 antikoerper, Tsp_07547 antikoerper, Tsp_07549 antikoerper, Narf antikoerper, narf antikoerper, narf.L antikoerper
    Hintergrund
    Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.
    Molekulargewicht
    51156
    Gen-ID
    26502
    NCBI Accession
    NP_001033707, NP_001077077, NP_036468, NP_114174
    UniProt
    Q9UHQ1
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