This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FBXO5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-221 amino acids from the Central region of human FBXO5.
EMI1 antikoerper, FBX5 antikoerper, Fbxo31 antikoerper, 2510044I10Rik antikoerper, C85305 antikoerper, Emi1 antikoerper, emi1 antikoerper, fc65h02 antikoerper, wu:fc65h02 antikoerper, wu:fe06e07 antikoerper, wu:fz79f03 antikoerper, zgc:136397 antikoerper, zgc:158541 antikoerper, fbx5 antikoerper, Fbxo5 antikoerper, ACYPI007854 antikoerper, fbxo5 antikoerper, F-box protein 5 antikoerper, F-box only protein 5 antikoerper, F-box protein 5 L homeolog antikoerper, F-box protein 5 S homeolog antikoerper, FBXO5 antikoerper, Fbxo5 antikoerper, fbxo5 antikoerper, fbxo5.L antikoerper, fbxo5.S antikoerper
Hintergrund
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.