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TFEB Antikörper (AA 271-300)

TFEB Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB39331 unconjugated
Produktnummer ABIN1538221
  • Target Alle TFEB Antikörper anzeigen
    TFEB (Transcription Factor EB (TFEB))
    Bindungsspezifität
    • 16
    • 9
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 271-300
    Reaktivität
    • 61
    • 30
    • 26
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 7
    Kaninchen
    Klonalität
    • 53
    • 7
    Polyklonal
    Konjugat
    • 37
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TFEB Antikörper ist unkonjugiert
    Applikation
    • 55
    • 31
    • 14
    • 13
    • 13
    • 12
    • 10
    • 9
    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TFEB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human TFEB.
    Klon
    RB39331
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TFEB Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    TFEB Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    TFEB (Transcription Factor EB (TFEB))
    Andere Bezeichnung
    TFEB (TFEB Produkte)
    Hintergrund
    Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.
    Molekulargewicht
    52865
    Gen-ID
    7942
    NCBI Accession
    NP_001161299, NP_001258872, NP_001258873, NP_001258874, NP_009093
    UniProt
    P19484
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